How to resolve the error - bad message 431 reason request header fields too large?

This happened to me today (Chrome - Developer Console), I received the error - bad message 431 reason request header fields too large - The issue was I had lots of code from previous Execute Anonymous sessions that had been commented out. As I added new lines to the top such as below, I pushed the character limit as sent via Tooling API past the max value

Lead[] leads = new list {
    new Lead(Company = 'Foo00', LastName = 'LName00'),
    new Lead(Company = 'Foo01', LastName = 'LName01')
    };
insert leads;
leads[0].Company = 'Foo00Changed';
leads[1].Company = 'Foo01Changed';
leads[1].Website = 'www.failme.com';  // force partial success by failing this in VR
Database.SaveResult[] results = Database.update(leads,false); // allow partial success
/*
many lines of code previously entered for prior tests. "Many" was in the hundreds
*/
By deleting some of those lines of commented out code, the error went away.